1.Introduction

Bacterial spores are the most resistant of all living organisms because of their capacity to withstand external destructive agents. Although the physical or chemical process by which all pathogenic and microorganisms, including spores, are destroyed is not absolute, supplies and equipment are considered sterile when necessary conditions have been met during a sterilization process.

2.Methods

Reliable sterilization depends on contact of the sterilizing agent with all surfaces of the item to be sterilized. Selection of the agent to achieve sterility depends primarily upon the nature of the item to be sterilized.

3.Ethylene Oxide

Ethylene oxide is used to sterilize items that are heat or moisture sensitive. Ethylene oxide (EO) is a chemical agent that kills microorganisms, including spores, by interfering with the normal metabolism of protein and reproductive, processes, (alkylation) resulting in death of cells. Used in the gaseous state, EO gas must have direct contact with microorganisms on or in items to be sterilized. Because EO is highly flammable and explosive in air, it must be used in an explosion-proof sterilizing chamber inn a controlled environment. When handled properly, EO is a reliable and safe agent for sterilization, but toxic emissions and residues of EO present hazards to personnel and patients. Also, it takes longer than steam sterilization, typically, 16-18 hrs. for a complete cycle.

EO gas sterilization is dependent upon four parameters: EO gas concentration, temperature, humidity, and exposure time. Each parameter may be varied. Consequently, EO sterilization is a complex multi-parameter process. Each parameter affects the other dependent parameters.

Our disposable nonwoven medical products are sterilized with EO. This sterile surgical packs , surgical drapes and surgical gowns can be used for one-time protection during operation and help the successful operation.